A non-coding CRHR2 SNP rs255105, a cis-eQTL for a downstream lincRNA AC005154.6, is associated with heroin addiction.
Dysregulation of the stress response is implicated in drug addiction; therefore, polymorphisms in stress-related genes may be involved in this disease.An analysis was performed to identify associations between variants in 11 stress-related genes, selected a priori, and heroin addiction.Two discovery samples of American subjects of European descent